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Finding natural, science-backed supplements for brain health can be difficult. Many of these supplements have been overly processed, some contain unnecessary additives, while others are purely pharmaceutical. New science emerging around the hemp plant shows promising results for cannabinoid supplements and memory. These studies point to solutions that improve the way the brain ages, rather than prevent and manage its age-related neurological decline.

CBN (cannabinol) is a minor cannabinoid found in the hemp plant that is thought to have potential medicinal properties, including sedative effects that may even make it helpful as a sleep aid. Research has also suggested that CBN may have potential benefits for memory health.

In 2018, researchers at the Salk Institute published a study in the journal Nature that examined the potential effects of CBN on the development of Alzheimer’s disease in mice. The study found that CBN was able to reduce the production of amyloid beta, a protein that is associated with the development of Alzheimer’s disease. The researchers also found that CBN was able to improve cognitive function and reduce inflammation in the brain in mice with Alzheimer’s disease.

In 2022, this same institute published a further study titled “Active ingredient in cannabis protects aging brain cells.” Researchers found CBN-protected nerve cells from oxidative stress, which is thought to be one of the drivers of neurological decline. They are working on reproducing these results in pre-clinical mouse models.

However, it is important to note that these studies were conducted both in vitro and in animal models, and more research is needed to fully understand the potential effects of CBN on memory health in humans. It is also important to consider that the use of CBN, and any other cannabinoid, is regulated and may not be available in all areas. It is always best to speak with a healthcare provider before starting any new supplement, including CBN.

While CBN may have the potential as a treatment for memory loss or cognitive decline, it is important to remember that maintaining good memory health is a complex process that involves a variety of factors, including diet, exercise, stress management, and social interaction. Incorporating a healthy lifestyle and engaging in activities that challenge the brain can also help to support memory health.